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Biphasic activation of renal afferent by intrarenal artery injection of bradykinin in anesthetized rabbits

Wu Yuming, He Ruirong

Department of Physiology,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

It is concluded that intrarenal BK induces a significant increase in ARNA in two phases. The early phase may be due to the direct action of BK and partially due to the NO action, while the delayed phase may be attributed to the action of released prostaglandin and NO as a result of intrarenal BK.

Key words: Bradykinin;Renal afferent nerve;Unit-activity;Indomethecin;L-NAME

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Citing This Article：

Wu Yuming, He Ruirong. Biphasic activation of renal afferent by intrarenal artery injection of bradykinin in anesthetized rabbits. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).