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Effect of chronic hypoxia on the calcium and potassium current of myocytes of the right ventricle in guinea pig

Bei Bihua, Zhang Zhenxiang, Xu Yongjian, Yue Yuankun, Tang Ming

Divisioni of Respiratory Medicine,Tongji Hospital,Tongji Medical University.Wuhan 430030,Hubei；China

Abstract

To explore the effect of chronic hypoxia on calcium and potassium currents of the right ventricle myocytes in the guinea pig, the cell membrane capacities, calcium and delayed rectifier potassium current were recorded using the whole-cell patch clamp technique from single right ventricle myocytes in guinea pigs under chronic hypoxia.

Key words: Pulmonary hypertension;Cardiomyocyte;Patch clamp;Calcium current;Delayed rectifier potassium current

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Citing This Article：

Bei Bihua, Zhang Zhenxiang, Xu Yongjian, Yue Yuankun, Tang Ming. Effect of chronic hypoxia on the calcium and potassium current of myocytes of the right ventricle in guinea pig. Acta Physiol Sin 1999; 51 (5): (in Chinese with English abstract).