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Role of red nucleus in inhibiting nociceptive responses of rat spindle afferent

Tang Bin, Fan Xiaoli, Wang Congying, Li Qiang

Department of Physiology,Xi^an Medical University.Xi^an 710061,Shaanxi

Abstract

Using extracellular recording techniques, the effect of excitation of red nucleus (RN) on C-responses of wide dynamic range (WDR) neurons and the roles of RN in the inhibitory effect of spindle afferent activated by succinycholine (SCH) on C-responses of WDR neurons were studied. Stimulation of RN caused a significant reduction of nociceptive responses of WDR neurons, which was significantly attenuated by intravenous cyproheptadine and contralateral lesion of RN.

Key words: Red nucleus;Wide dynamic range neurons;Muscle spindle;Analgesia

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Citing This Article：

Tang Bin, Fan Xiaoli, Wang Congying, Li Qiang. Role of red nucleus in inhibiting nociceptive responses of rat spindle afferent. Acta Physiol Sin 1999; 51 (4): (in Chinese with English abstract).