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Destruction of NA innervation in the rat hippocampus resists the hypoxia-induced corticosterone secretion

Zhu Xiaoman, Zhu Zitao, Wen Chuanjun, Zhou Yuqian

Department of Physiology,Nanjing Railway Medical College.Nanjing 210009,Jiangsu

Abstract

The plasma CS response to inhalation of 10.4% O_(2) (30 min) was increased markedly; while the plasma CS level and the noradrenaline (NA) contents in hippocampus were decreased (-33.2% and -38.5%, respectively) 2 weeks after microinfusion of 6-OHDA (8 #mu#g/2 #mu#l) into VHIP; however, the CS response to acute hypoxia was unaffected by 6-OHDA lesion of VHIP.

Key words: Hypoxia;Corticosterone;Hippocampus;6-hydroxydopamine (6-OHDA)

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Citing This Article：

Zhu Xiaoman, Zhu Zitao, Wen Chuanjun, Zhou Yuqian. Destruction of NA innervation in the rat hippocampus resists the hypoxia-induced corticosterone secretion. Acta Physiol Sin 1999; 51 (3): (in Chinese with English abstract).