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Detection of release of aspartate and glutamate in cat spinal dorsal horn following noxious stimulation of cutaneous and muscular afferent fibers using microdialysis

Song Xuejun, Shu Yousheng, Yin Pingbo, Zhao Zhiqi

Shanghai Brain Research Institute,Chinese Academy of Sciences.Shanghai 200031；China

Abstract

Asp and Glu were increased respectively by (323±55)% and (169±16)% following stimulation of cutaneous nerve, but by (150±16)% and (218±42)% respectively following stimulation of muscular nerve. Asp increase was approximately three times higher than that of Glu following cutaneous nerve-stimulation (P<0.01), while Glu increase was approximately twice as high as that of Asp following muscular nerve-stimulation (P<0.05).

Key words: Glutamate;Aspartate;Microdialysis;Spinal nociception

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Citing This Article：

Song Xuejun, Shu Yousheng, Yin Pingbo, Zhao Zhiqi. Detection of release of aspartate and glutamate in cat spinal dorsal horn following noxious stimulation of cutaneous and muscular afferent fibers using microdialysis. Acta Physiol Sin 1999; 51 (3): (in Chinese with English abstract).