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Effect of #beta#-endorphin on plasma sialic acid level in rats and the relationship with the immune function

Chen Wenfang, Chen Lei, Lu Xiuwen, Chen Jiajin

Department of Physiology,The Medical College of Qingdao University.Qingdao 266021,Shandong

Abstract

The plasma SA level was significantly decreased after microinjection of #beta#-EP into the lateral ventricle (LV); When #beta#-EP was microinjection into nucleus arcuatus (ARC), the plasma SA level was significantly decreased (P<0.05). This effect can be blocked by i.v. atropine or vagotomy; Microinjection of #beta#-EP into ARC can cause the increase of CD3, CD4 and CD4/CD8, while CD8 was decreased.

Key words: Plasma;Sialic acid;#beta#-endorphin;Lateral ventricle;Nucleus arcuatus;Lymphocyte rat;

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Citing This Article：

Chen Wenfang, Chen Lei, Lu Xiuwen, Chen Jiajin. Effect of #beta#-endorphin on plasma sialic acid level in rats and the relationship with the immune function. Acta Physiol Sin 1999; 51 (3): (in Chinese with English abstract).