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Effect of lipopolysaccharide on the proliferation of rat VSMCs in vitro

Li Jian, Lin Shuxin, Li Ying, Zhao Heling, Jia Bin

Department of Pathophysiology,The Fourth Military Medical University.Xi^an 710032,Shaanxi

Abstract

LPS of low dose stimulated the proliferation and the DNA synthesis of VSMCs, while LPS of high dose markedly inhibited them probably due to the increased NO production.

Key words: lipopolysaccharide(LPS);Vascular smooth muscle cells;Proliferation;Nitric oxide(NO)

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Citing This Article：

Li Jian, Lin Shuxin, Li Ying, Zhao Heling, Jia Bin. Effect of lipopolysaccharide on the proliferation of rat VSMCs in vitro. Acta Physiol Sin 1999; 51 (1): 14-18 (in Chinese with English abstract).