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Opioid receptor mediated modulation of intrahippocampal enkephalin induced cellular immune function

Gao Na, Wang Ajing, Yang Yuzhen, Hu Mouxian, Xie Hong

Department of Physiology,Capital University of Medical Sciences.Beijing 100054；China

Abstract

In the present work, the effect of intrahippocampal microinjection of opioid receptor antagonist naloxone on the enhancement of cellular immune responses induced by enkephalin was studied in rat. The results suggest that the enhancement of cellular immune responses induced by enkephalin was mediated by opioid receptors in hippocampus.

Key words: Neuroimmunomodulation;Hippocampus;Enkephalin;Opioid receptor

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Citing This Article：

Gao Na, Wang Ajing, Yang Yuzhen, Hu Mouxian, Xie Hong. Opioid receptor mediated modulation of intrahippocampal enkephalin induced cellular immune function. Acta Physiol Sin 1999; 51 (1): 106-110 (in Chinese with English abstract).