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The sub-cellular distribution of #beta#-catenin in the neural differentiation of RA induced P19 EC cells

Yang Jing, Hou Haiyu, Bian Wei, Lin Qishui, Jing Naihe

Shanghai Institute of Biochemistry,Chinese Academy of Sciences.Shanghai 200031

Abstract

Wnt signals have been shown to play an important role in the development of the central nervous system (CNS) of mouse. In our previous work, it was demonstrated that Wnt signal could initiate differentiation of P19 EC cells. In the present investigation, it was examined with RT-PCR whether expression of #beta#-catenin, a downstream gene of Wnt in its signal transduction pathway, is regulated.

Key words: Wnt;#beta#-catenin;P19 EC cells;Neuronal differentiation

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Citing This Article：

Yang Jing, Hou Haiyu, Bian Wei, Lin Qishui, Jing Naihe. The sub-cellular distribution of #beta#-catenin in the neural differentiation of RA induced P19 EC cells. Acta Physiol Sin 1998; 50 (6): (in Chinese with English abstract).