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Effects of glycine and strychnine microinjected into unilateral and bilateral Botzinger complex on phrenic nerve discharges in rabbits

Lu Ming, Li Qin, Song Gang, Zhang Heng, Liu Lei

Department of Physiology,Shandong Medical University.Jinan 250012,Shandong

Abstract

The effects of microinjection of glycine and strychnine into unilateral and bilateral Botzinger complex (Bot.C) on phrenic nerve discharges were observed in 34 urethane anaesthetized, vagotomized, paralyzed and artificially ventilated rabbits. The results suggest that the Bo.C plays a crucial role in initiating and sustaining expiration.

Key words: Botzinger complex;Phrenic nerve discharges;Microinjection;Glycine;Strychnine

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Citing This Article：

Lu Ming, Li Qin, Song Gang, Zhang Heng, Liu Lei. Effects of glycine and strychnine microinjected into unilateral and bilateral Botzinger complex on phrenic nerve discharges in rabbits. Acta Physiol Sin 1998; 50 (6): (in Chinese with English abstract).