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Effects of NO and endothelium on carotid baroreceptor activity

Xia Linying, Niu Weizhen, Shen Jing, Liu Beiying

Department of Cardiovascular Physiology,Capital University of Medical Sciences.Beijing 100054

Abstract

The present study was undertaken to examine the effects of endothelium and exogenous NO on the baroreceptor discharge of the carotid sinus. The baroreceptor activity (BRA) was recorded from the rabit carotid sinus-sinus nerve (CS-CSN) preparation using a chamber for superfusing and perfusing the tissue. Results indicate that stimulation of BRA by exogenous NO may be mediated by the endothelium, but cGMP dose not seem to be involved.

Key words: Baroreceptor;Nitric oxide;Endothelium;Carotid sinus;Rabbit

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Citing This Article：

Xia Linying, Niu Weizhen, Shen Jing, Liu Beiying. Effects of NO and endothelium on carotid baroreceptor activity. Acta Physiol Sin 1998; 50 (6): (in Chinese with English abstract).