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Effects of endothelin on carotid baroreceptor activitity in anesthetized rats

Abstract

ET-1 exerts the dual effects on baroreceptor, facilitation at low doses and inhibition at high doses. The later effect may be mediated by ET_(A) through K_(ATP) channels.

Key words: Endothelin-1;Baroreceptor activity;Carotid sinus afferent discharge;K_(ATP) channels

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Citing This Article：

. Effects of endothelin on carotid baroreceptor activitity in anesthetized rats. Acta Physiol Sin 1998; 50 (5): (in Chinese with English abstract).