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Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy

Abstract

The results clearly demonstrated that labyrinthectomy increased GAP-43 mRNA expression to different extents and amplitudes in bilateral medial vestibular nuclei. This finding suggests that upregulation of GAP-43 mRNA expression is related to regenerative sprouting, synaptic remodeling and neuroplasticity in vestibular compensation.

Key words: Growth-associated protein (GAN-43);Vestibular compensation;Neuroplasticity;In situhybridization

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Citing This Article：

. Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy. Acta Physiol Sin 1998; 50 (5): (in Chinese with English abstract).