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Regulatory effect of hepatic stimulator substance on the proliferation of human hepatoma cells

Abstract

The hepatic stimulator substance (HSS) was prepared from weanling rat livers by ultracentrifugation and Sephadex G-75 chromatography. The stimulatory effects of HSS on cell proliferation, EGF receptor expression and receptor tyrosine phosphorylation were investigated in serum-free cultured human hepatoma cell line SMMG-7721.

Key words: Hepatic stimulator substance;EGF receptor;Hepatocyte proliferation

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Citing This Article：

. Regulatory effect of hepatic stimulator substance on the proliferation of human hepatoma cells. Acta Physiol Sin 1998; 50 (5): (in Chinese with English abstract).