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Expression of calcitonin gene-related peptide (CGRP) mRNA in rat lymphocytes

Abstract

We recently found that calcitonin gene-related peptide (CGRP)-like immunoreactivity was present in lymphocytes of rat thymus and lymph node. In order to investigate whether these cells were capable of synthesizing CGRP, CGRP mRNA of rat dorsal root ganglia, thymocytes and mesenteric lymph node lymphocytes were determined by reverse transcription and polymerase chain reaction (RT-PCR) utilizaing synthetic oligonucleotides bracketing a portion of the calcitonin/CGRP gene.

Key words: Calcitonin gene-related peptide;mRNA;Reverse transcription;Polymerase chain reaction

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Citing This Article：

. Expression of calcitonin gene-related peptide (CGRP) mRNA in rat lymphocytes. Acta Physiol Sin 1998; 50 (4): (in Chinese with English abstract).