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Regulatory role of 5-hydroxytryptamine and motilin in migrating motor complex of small bowel in dogs

Abstract

Migrating motor complex (MMC) was recorded by chronically implanted strain gauge transducers on the serosa of small bowel in conscious dogs. Two silastic catheters for injecting drugs and taking blood samples were put respectively in a vena jugularis extema and in a jejunal artery which perfused a 10-15 cm intestinal segment. The present study was undertaken to observe the effect of drugs administered intravenously and intra-arterially on MMC and alterations of plasma 5-hydroxytryptamine (5-HT) and motilin in different phases of MMC.

Key words: Migrating motor complex;5-hydroxytryptamine;Motilin

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Citing This Article：

. Regulatory role of 5-hydroxytryptamine and motilin in migrating motor complex of small bowel in dogs. Acta Physiol Sin 1998; 50 (4): (in Chinese with English abstract).