ISSN 0371-0874, CN 31-1352/Q

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Regulation of ACTH_(4-9) analogue on the Ca~(2+) level of mouse hippocampal synaptosomes

Abstract

Low dose of Org2766 did not change synaptosomal [Ca~(2+)]_(i) level, but decreased ~(45)Ca~(2+) uptake. High dose of Org2766 increased [Ca~(2+)]_(i) without affecting ~(45)Ca~(2+) uptake. Low dose of Org2766 inhibited the anisomysin-induced increase of synaptosomal [Ca~(2+)]_(i) while high dose had no effect.

Key words: ACTH_(4-9)analogUe Org2766;Hippocampal synaptosomes;Fure-2;[ Ca~(2+)]_(i); ~(45)Ca~(2+)uptake

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Citing This Article:

. Regulation of ACTH_(4-9) analogue on the Ca~(2+) level of mouse hippocampal synaptosomes. Acta Physiol Sin 1998; 50 (4): (in Chinese with English abstract).