ISSN 0371-0874, CN 31-1352/Q

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Neural differentation of Wnt-1 overexpression P19 cells

Abstract

Wnt-1 gene plays important roles during the development of the mouse central neural system, and shown a transient expression during neuronal differentiation of P19 EC cells. We transfected Wnt-1 gene into P19 cells and found the Wnt-1 transfected cells could differentiate into neurons without the induction of RA. However, MASH-1, a crucial gene for the early neural differentiation, was expressed later than P19 cells induced by RA.

Key words: Wnt-1;Reverse transcriptional PCR;P19 cells;Overexpression;Neuronal differentiation;MASH-1

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Citing This Article:

. Neural differentation of Wnt-1 overexpression P19 cells. Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).