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Effect of orphanin FQ on acupuncture analgesia and noxious stimulation in the periaqueductal gray

Abstract

The results show that the hyperalgesia of OFQ and its antagonization on AA in PAG are dose-related. OFQ in PAG decreases the enhancing effect on AA induced by ohmefentanyl, a selective #mu#-receptor agonist. These observations suggest that OFQ in PAG can increase the rat pain sensitivity and antagonize AA.

Key words: Orphanin Fo;#mu#-receptor;Acupuncture;Analgesia;Pain

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Citing This Article：

. Effect of orphanin FQ on acupuncture analgesia and noxious stimulation in the periaqueductal gray. Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).