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In vitro growth characteristics of rIL_(3) stimulated megakaryocytic progenitor cells (CFU-MK) or fetal liver

Ma Dongchu, Sun Yinghui, Chang Kuizhong

Department of Experimental Medicine, General Hospital of Shenyang. Shenyang 110015, Liaoning

Abstract

In this study, plasma clot and methycellulose semi-solid and liquid culture technigues were employed to observe the in vitro growth characteristics of proliferation and differetiation of 4-5 months fetal liver and adult bone marrow CFU-MKs. Fetal liver MK colonies in plasma clot in the presence of rIL_(3) or Meg-CSA were larger (usually with >50 cells/colony) than that of the adult (usually with<50 cells/colony).

Key words: Megakaryocytes;DNA ploidy;CFU-MK;fetal liver

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Citing This Article：

Ma Dongchu, Sun Yinghui, Chang Kuizhong. In vitro growth characteristics of rIL_(3) stimulated megakaryocytic progenitor cells (CFU-MK) or fetal liver. Acta Physiol Sin 1997; 49 (2): (in Chinese with English abstract).