L-arginine transport in cultured vascular smooth muscie cells of spontaneously hypertensive rats and effect of liposome on the transport
Yao Xinghai, Lu Xiaoyan, Zhang Lingzhi, Niu Dadi, Gao Lianru, Pang Yongzheng, Su Jingyi, Tang Chaoshu
Institute of Cardiovascular Basic Research Beijing Medical University. Beijing 100083;China;Cardiology Department, Naval General Hospital.Beijing 100037
Abstract
There exists a functional disturbance in L-Arg transport in the SMC of SHR, but the L-Arg transport in SMC can be obviously enhanced when liposome is used as L-Arg carrier. Thus, it appears that liposome-L-Arg may have clinical perspective in the treatment of hypertension.
Key words: Hypertension;L-Arginine;Smooth muscle cells;Liposome
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Yao Xinghai, Lu Xiaoyan, Zhang Lingzhi, Niu Dadi, Gao Lianru, Pang Yongzheng, Su Jingyi, Tang Chaoshu. L-arginine transport in cultured vascular smooth muscie cells of spontaneously hypertensive rats and effect of liposome on the transport. Acta Physiol Sin 1997; 49 (1): (in Chinese with English abstract).