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Relative changes between calcium content and number of atrial specific granules induced by water and salt loading

Yu Zhang, Zhong Cisheng

Department of Biophysics, Shanghai Medical University. Shanghai 200032

Abstract

In the drinking 2% NaCl solution group, the Nv of ASG decreased from 6.02±2.30 to 2.96±1.62/#mu#m~(3)(P<0.01) and all companied by a decrease of Ca concentration from 64±16 to 38±21mmol/kg (P<0.01), while the secretion of atrial natriuretic peptide (ANP) showed some increase. Water deprivation induced all the contrary results. However, the Ca concentration in TSR was not affected by water-salt loading. It considered that ASG as an intracellular Ca store participates in the stimulus-secretion coupling of ANP through the release of Ca ions.

Key words: Atrial specific granule;Water-depriving;Salt-loading;Intracellular Ca store

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Citing This Article：

Yu Zhang, Zhong Cisheng. Relative changes between calcium content and number of atrial specific granules induced by water and salt loading. Acta Physiol Sin 1995; 47 (5): (in Chinese with English abstract).