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Measurement of rCBF by hydrogen gas clearance with lower H_(2) concentration in rats

Zhong Kaisheng, Lu Min, Gu Zhengzhong

Shanghai Institute of Physiology, Chinese Academy of Sciences. Shanghai

Abstract

It was found that 3% H_(2) which is lower than the lower concentration limit guarded against occurrence of explosion could be mixed with any concentration ratio of N_(2)to O_(2) without causing transient hypoxia as ofthe found by inhaling 100% H_(2) and thus made clearance measurement more accurate and safe. Comparison studies between inhaling 100% H_(2) and 3% H_(2) as well as inhaling 3% H_(2) for 1-1.5 min and 3% H_(2) for 5min were undertaken. Repeated measurements of 3% H_(2) clearance for 1.5 min further showed that celarance test using low H_(2) concentration for short term periods reflected better the rCBF of experimental animals.

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Citing This Article：

Zhong Kaisheng, Lu Min, Gu Zhengzhong. Measurement of rCBF by hydrogen gas clearance with lower H_(2) concentration in rats. Acta Physiol Sin 1994; 46 (3): (in Chinese with English abstract).