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Detection of messenger RNA coding for BNP precursor in rat brain by in situ hybridization

Liu Jing, Ma Yong, Li Jing, Zhang Aimin, Liu Hong, Xu Xun

Department of Biology, University of Science and Technology of China. Hefei,Anhui

Abstract

Messenger RNA coding for BNP precursor has been detected and mapped in histological sections of rat brain by in situ hybridization using specific rat BNPDNa probes labelled with ~(32)P. The results showed that area of highest concentration of BNP gene expression were located in the hypothalamus and in the verge area of the thalamus.Sucesscively decreased concentration could also be found in amydaloid nuclei, olfactory bulb, hippocampus and cerebral cortex.

Key words: Brain natriuretic peptide(BNP);In-situ hybridization;Rat brain;mRNA

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Citing This Article：

Liu Jing, Ma Yong, Li Jing, Zhang Aimin, Liu Hong, Xu Xun. Detection of messenger RNA coding for BNP precursor in rat brain by in situ hybridization. Acta Physiol Sin 1994; 46 (2): (in Chinese with English abstract).