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Effects of alpha-adrenoreceptor excitation on the delayed after-depolarization of sheep cardiac Purkinje fibers

Bao Rende, Li Cizhen, Liu Yuanmou, Xu Youqiu

Department of Physiology, Shanghai Second Medical University. Shanghai

Abstract

By using acetyl strophanthidin 0.2#mu#mol/L, the delayed after depolartization was induced in sheep cardiac purkinje fibers and recorded woth intra-cellular microoelectrode. The reslts indicate that excitation of alph-receptor had only slight augmentation effect on DAD. However, for the triggered activity induced by DAD, the inhibitory effect ofbeta-blockers are stronger than that alpha-blockers.

Key words: Delayed aftsr-depolarization;Cardiac Purkinje fibers;Acetyl strophanthidin;#alpha#-adrenoceptor

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Citing This Article:

Bao Rende, Li Cizhen, Liu Yuanmou, Xu Youqiu. Effects of alpha-adrenoreceptor excitation on the delayed after-depolarization of sheep cardiac Purkinje fibers. Acta Physiol Sin 1994; 46 (2): (in Chinese with English abstract).