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Bradykinin inhibits carotid sinus baroreflex in anesthetized rats

Wu Yuming, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The effects of bradykinin (BK) on the carotid baroreflex were examined in 36 anesthetized rats with isolated carotid sinus perfusion. The results indicated that BK may cause vascular endothelium to release NO, thereby inhibiting the carotid baroreflex.

Key words: Bradykinin;Carotid sinus;Baroreflex;Mean arterial pressure;Intrasinus pressure

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Citing This Article：

Wu Yuming, He Ruirong. Bradykinin inhibits carotid sinus baroreflex in anesthetized rats. Acta Physiol Sin 1999; 51 (3): (in Chinese with English abstract).