Current Issue

Special issue on circadian rhythms in physiology and diseases—preface

CHEN Li-Hong^1,*, LI Min-Dian², YANG Guang-Rui³

¹1Health Science Center, East China Normal University, Shanghai 200241, China；²The First Affiliated Hospital of Army Medical University, Chongqing 400038, China；³School of Basic Medical Sciences, Shanghai University of Medicine & Health Sciences, Shanghai 201318, China

Abstract

The circadian rhythm is an internal mechanism evolved by the body to adapt to periodic changes in the environment. Among them, the rhythm with a cycle of about 24 hours has been extensively and deeply studied, and its relationship with human health is also the closest. The circadian rhythm exists in the vast majority of tissues and organs in the body, and its precise regulation is crucial for maintaining physiological homeostasis. A large amount of evidence shows that long-term disruption of the circadian rhythm is closely related to metabolic diseases, cardiovascular diseases, neurodegenerative changes, tumors, and even aging. In recent years, with the in-depth analysis of the molecular mechanisms of the circadian rhythm and the continuous advancement of its association with various diseases, chronobiology has become a cutting-edge field in physiology and medicine research. In this issue of the Journal of Physiology, Special Issue on Circadian Rhythms in Physiology and Diseases has been planned, inviting multiple domestic experts and scholars to write articles to systematically present the latest developments in this field through 9 reviews and 2 original articles.

Received: 　　Accepted:

Corresponding author: 陈丽红　　E-mail:

DOI: 10.13294/j.aps.2025.0071

Citing This Article：

CHEN Li-Hong, LI Min-Dian, YANG Guang-Rui. Special issue on circadian rhythms in physiology and diseases—preface. Acta Physiol Sin 2025; 77 (4): 603-604 (in Chinese with English abstract).