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Research progress on the effects and mechanisms of electroacupuncture on radiation- induced brain injury

WU Xin, LI Yan-Hui, GAO Jian-Feng^*

Department of Physiology, School of Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China

Abstract

Radiation-induced brain injury is a serious complication after cranio-cerebral radiotherapy, which affects the patient’s quality of life and survival. A large number of studies have shown that various mechanisms such as neuronal apoptosis, blood-brain barrier damage, and synaptic dysfunction may be related to radiation-induced brain injury. Acupuncture has an important role in clinical rehabilitation of various brain injuries. As a new type of acupuncture, electroacupuncture has the characteristics of strong control ability, uniform and long-lasting stimulation, and is widely used in clinic. This article reviews the effects and mechanisms of electroacupuncture on radiation-induced brain injury, in order to provide a theoretical basis and experimental support for reasonable clinical application.

Key words: radiation-induced brain injury; electroacupuncture; neural stem cells; learning and memory; synaptic plasticity

Received: 　　Accepted:

Corresponding author: 高剑峰　　E-mail:

DOI: 10.13294/j.aps.2023.0001

Citing This Article：

WU Xin, LI Yan-Hui, GAO Jian-Feng. Research progress on the effects and mechanisms of electroacupuncture on radiation- induced brain injury. Acta Physiol Sin 2023; 75 (1): 108-114 (in Chinese with English abstract).