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The relationship between brain networks and symptoms of schizophrenia

LIANG Jia-Lin¹, XIE Ye², KU Yi-Xuan^2,*

¹School of Psychology, Shenzhen University, Shenzhen 518067, China；²Brain and Mental Well-being Center, Department of Psychology, Sun Yat-sen University, Guangzhou 510006, China

Abstract

The pathogenesis of schizophrenia (SCZ) is not yet clear, and the pathological changes of the brain activity remains debatable. There are still numerous unresolved issues and debates regarding the relationship between functional connection of the brain network and the symptoms of SCZ. In this paper, we provide a comprehensive review of recent research progresses on resting-state and task-based brain networks, which covers the symptoms of SCZ. Furthermore, we discuss the relationship between large-scale brain networks and SCZ symptoms, and propose possible future research directions in the field of SCZ diagnosis and treatment.

Key words: Schizophrenia; brain network; symptoms; resting-state fMRI; task-based fMRI

Received: 2020-09-13　　Accepted: 2021-03-11

Corresponding author: 库逸轩　　E-mail: kuyixuan@mail.sysu.edu.cn; kuyixuan@gmail.com

DOI: 10.13294/j.aps.2021.0034

Citing This Article：

LIANG Jia-Lin, XIE Ye, KU Yi-Xuan. The relationship between brain networks and symptoms of schizophrenia. Acta Physiol Sin 2021; 73 (3): 446-458 (in Chinese with English abstract).