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Progresses on the effects and mechanisms of stress on gut microbiota

SONG Li-Jin, ZHANG Jin-Dong, DUAN Li-Ping^*

Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China

Abstract

Stress is the non-specific systemic response that occurs when the body is stimulated by various factors, and it can affect multiple systems of the body. Recent studies have shown that gut microbiota is an essential part of human microecology, and plays a pivotal role in keeping the body healthy. Stress can result in gut dysbiosis by affecting the function of intestinal mucosal barrier, intestinal immune and gastrointestinal motility. This article reviewed the alteration of gut microbiota caused by stress and the possible mechanisms involved.

Key words: Stress; gut microbiota; probiotics

Received: 2019-10-23　　Accepted: 2020-01-02

Corresponding author: 段丽萍　　E-mail: duanlp@bjmu.edu.cn

DOI: 10.13294/j.aps.2020.0031

Citing This Article：

SONG Li-Jin, ZHANG Jin-Dong, DUAN Li-Ping. Progresses on the effects and mechanisms of stress on gut microbiota. Acta Physiol Sin 2020; 72 (3): 361-370 (in Chinese with English abstract).