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[Progress in electrophysiological studies of retinal ganglion cells.] [Article in Chinese]

ZHOU Xu-Jiao, WANG Zhong-Feng, WU Ji-Hong

Research Center, Department of Ophthalmology at Eye &； ENT Hospital, Fudan University, Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China； Institutes of Brain Science, Fudan University, Shanghai 200032, China

Abstract

The knowledge about electrophysiological properties of retinal ganglion cells (RGCs), as well as modulation of these properties, is important not only for understanding the unique physiological functions of RGCs under normal conditions, but also for exploring the cellular mechanisms of retinal neurodegeneration diseases, such as glaucoma. In this paper, we reviewed the progress in electrophysiological studies of RGCs by using patch-clamp techniques, concerning the voltage-gated ion channels, the ligand-gated ion channels and the effects of neuromodulators on these channels.

Key words: retinal ganglion cell; voltage-gated ion channels; ligand-gated ion channels; neuromodulator

Received: 2014-04-08　　Accepted: 2014-06-17

Corresponding author: 王中峰,吴继红　　E-mail: lwnn2006@gmail.com, zfwang@fudan.edu.cn

Citing This Article：

ZHOU Xu-Jiao, WANG Zhong-Feng, WU Ji-Hong. [Progress in electrophysiological studies of retinal ganglion cells.] [Article in Chinese]. Acta Physiol Sin 2014; 66 (5): 511-518 (in Chinese with English abstract).