Issue Archive

Cui Hong

First Clinical Institute，China Medical University. Shenyang 110001,Liaoning, China

Abstract

On 10 New Zealand White rabbits irnmohilized with Flaxedil, the inhihitory effect of alnygdaloid stimulation on the responses of medial geniculate body (MGB) neurons to tone bursts and the involved neurotransndtter mechanism were investigated with microiontophoresis techniqUe. 'foe results showed that application of GABA could cause a suppression of spontaneous activity of MGB neurons while GABAA antagonist bicuculline had an opPOsite effect. Iontophoretic injection of GABA gave an inhibitory effect on MGB neurons similar to that caused by stimulating foe amygdala or the auditory cortex behind the thinal sulcus (ACBRS), and in particular, the GABA induced suppression could be completely antagonized by application of hicuculline. Taken together, these data suggested that GABA mediated the amygdaloid inhibitory effect. It seemed unlikely that glycine was involved in the effect, since strychnine, a glycine antagonist, could not affect the descending inhibition from ACBRS area.

Key words: ;;;

Received: 　　Accepted:

Corresponding author: 　　E-mail:

Citing This Article：

Cui Hong. . Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).