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RENIN-ANGIOTENSION SYSTEM —STRESS HORMONE RESPONSE SYSTEM

Wan Yu, Yang Gang, WAN SHU-XIA, YANG BO, PING YAN-RU , XI ZHENG-XIONG

(Department of Physiology, Hubei Medical University, Wuhan 430071)

Abstract

Angiotensin B (A Ⅱ)was significantly increased in both acutely and chronically stressed animals as found in brain，heart，blood vessels and adrenal glands. After running a race，the plasma A } contents of sportsmen similar to cortisol increased marked1y too. In the chronical stress-hypertensive animals，the contents of circulating A Ⅱ and tissue A Ⅱ were increased quite lastingly. It was also found that the high concentration
of A Ⅱ may stimulate the adrenal gland secreting glucosteroid，and increase of tissue A ff may be faciliated by the activation of beta adrenergic receptors. On basis of the above finding，we tend to assume that A IC is a stress hormone and the renin angiotension system (RAS) is a stress hormone responses system. Morever there exists a close relation between RAS and two classic stress hormone response systems, i. e. the hypothalamus-pituitary-adrenal cortex system and the sympathetic-adrenal medulla system.

Key words: angiotensin;Stress;renin-angiotensin-system;Cortisol;hypothalamuspituitary adrenal cortex;sympathetic-adrenal medulla system;stress hormone responses system

Received: 　　Accepted:

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Citing This Article：

Wan Yu, Yang Gang, WAN SHU-XIA, YANG BO, PING YAN-RU , XI ZHENG-XIONG. RENIN-ANGIOTENSION SYSTEM —STRESS HORMONE RESPONSE SYSTEM. Acta Physiol Sin 1996; 48 (6): (in Chinese with English abstract).