Issue Archive

EFFECT OF INTESTINAL LYMPH ON BLOOD PRESSURE OF RAT

ZHANG JING, LIU YAN-KAI, JIANG HUA, GE LIN, SHI MAN-JIN, ZHANG LI-MING

(Department of Pathophysiology, Zhangjiakou Medical College, Zhangjiakou 075029)

Abstract

The effect of intestinal lymph on blood pressure in rats was observed by the methods of lymph drainage and lymph infusion. The results obtained are as follows:(1)After 150 min of the lymph drained through the cannula of intestinal lymph duct，the blood pressure was significantly lower than that of the sham group (P<0. 05).(2) Equivalent albumin or intralipid infusion was not able to prevent the decrease in blood pressure when the lymph was lost. But in jugular-intestinal lymph duct shunt group，no significant blood pressure decrease could be seen during the drainage procedure for 4 h: (3) The blood pressure of rat with serious hemorrhagic shock could be increased significantly with a little amount of intestinal lymph infusion，and the rats survived longer than those of the control group (P<0. 05-0. 01).The above results suggest that the intestinal lymph may play an important role in maintenance of blood pressure，in addition to the known function of lymphatic system by returning tissue fluid to blood and maintaining circulating blood volume.

Key words: intestinal lymph;Blood pressure;shock;regulation

Received: 　　Accepted:

Corresponding author: 　　E-mail:

Citing This Article：

ZHANG JING, LIU YAN-KAI, JIANG HUA, GE LIN, SHI MAN-JIN, ZHANG LI-MING. EFFECT OF INTESTINAL LYMPH ON BLOOD PRESSURE OF RAT . Acta Physiol Sin 1997; 49 (4): (in Chinese with English abstract).