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The role of central arginine vasopressin in corticotropin releasing hormone-induced fever in rats

Wang Huadong, Wang Yanping, Hu Chaofeng, Qi Renbin, Yan Yuxia, Lu Daxiang, Li Chujie

Departments of Pathophysiology,Medical College of Jinan University.Guangzhou 510632,Guangdong；China

Abstract

The purpose of the present study was to investigate the role of central arginine vasopressin (AVP) in corticotropin releasing hormone (CRH)-induced fever in the rat. Guide cannulae were inserted into the third ventricle and placed over the ventral septal area (VSA). The content of arginine vasopressin in the VSA of the brain was determined by radioimmunoassay. Colon temperature was monitored in lightly restrained rats by insertion of a catheter-mounted thermistor probe 5 cm in the rectum.

Key words: Corticotrophin releasing hormone;Arginine vasopressin;Fever;Thermoregulation

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Citing This Article：

Wang Huadong, Wang Yanping, Hu Chaofeng, Qi Renbin, Yan Yuxia, Lu Daxiang, Li Chujie. The role of central arginine vasopressin in corticotropin releasing hormone-induced fever in rats. Acta Physiol Sin 2001; 53 (6): (in Chinese with English abstract).